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What is the purpose of a female infertility work-up?
The purpose is to identify potential causes of infertility by evaluating factors such as ovulation, ovarian reserve, uterine health, and tubal patency. It helps tailor treatment strategies for achieving pregnancy.
What tests are commonly included in a female infertility evaluation?
Tests often include hormone panels, ultrasound, HSG (hysterosalpingogram), and semen analysis for your partner.
How long should I try to conceive before seeking an infertility work-up?
If you’re under 35, try for 12 months; if you’re over 35, consider testing after 6 months.
Can lifestyle factors affect the results of an infertility work-up?
Yes—factors like smoking, weight, and stress can impact fertility measurements.
Are infertility work-ups painful or invasive?
Most tests are minimally invasive and well-tolerated. Your doctor will guide you through each step.
What is a blastocyst in the context of IVF?
A blastocyst is an embryo developed in the lab for 5–6 days, reaching a more advanced stage of growth with higher implantation potential compared to earlier stage embryos.
Why is blastocyst culture and transfer preferred over day-3 embryo transfer?
Blastocysts better mimic natural development and often show which embryos are most viable.
Does every embryo reach the blastocyst stage during culture?
No, only the most robust embryos typically make it to blastocyst.
Is blastocyst transfer riskier than earlier-stage embryo transfer?
No – it’s a standard and safe procedure when done in experienced labs.
Can blastocyst culture improve the chances of a healthy pregnancy?
Yes, by selecting embryos with higher implantation potential.
Who typically benefits from a donor oocyte programme?
Women with poor ovarian reserve, genetic conditions, or repeated IVF failures often benefit.
How are donor eggs selected for compatibility?
Through thorough medical, genetic, and psychological screening of donors.
Does using donor eggs affect the baby’s genetics?
No, the baby’s genetics come from the donor egg and the partner’s sperm.
What ethical challenges might arise in using donor eggs?
Consent, anonymity, and long-term follow-up can present ethical considerations.
Can donor oocyte programmes support ethical and cultural sensitivities?
Yes—programmes follow strict guidelines to respect all parties.
What is a DNA Fragmentation Index (DFI) test?
The DFI test assesses the percentage of sperm with fragmented DNA, which can impair fertilization and embryo quality during conception.
Why is the DFI test important in fertility evaluations?
High DFI can lead to poor fertilization rates, embryo arrest, or miscarriage.
What causes high DNA fragmentation in sperm?
Oxidative stress, infection, smoking, and lifestyle factors.
Can high DFI levels be treated or improved?
Yes—antioxidant therapy, lifestyle changes, and certain medical treatments can help.
When is the DFI test recommended?
After repeated IVF failures or recurrent pregnancy loss.